Real Madrid overpowered Liverpool 3-1 in the first leg of the sides' Champions League quarterfinal on Tuesday, while Borussia Dortmund was left frustrated by a disallowed goal in its 2-1 defeat to Manchester City.
Despite being without starting center-back pairing Sergio Ramos and Raphael Varane, Real Madrid looked a class above the reigning Premier League champion and took the lead through first-half goals from Vinicius Junior and Marco Asensio.
Mohamed Salah pulled one back for Liverpool, but with 25 minutes remaining, Real extended its lead with Vinicius grabbing his second of the night.
It was the same scoreline as when the two sides met in the Champions League final in 2018, and this time Liverpool faces a tough challenge to overturn the two-goal deficit in the second leg at Anfield on April 14.
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"If you want to go to the semifinals of the Champions League, you have to earn the right to do so," Liverpool manager Jurgen Klopp told BT Sport.